KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS15
All Species:
25.76
Human Site:
S147
Identified Species:
56.67
UniProt:
P42566
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P42566
NP_001153441.1
896
98656
S147
S
P
V
N
G
F
L
S
G
D
K
V
K
P
V
Chimpanzee
Pan troglodytes
XP_001139393
896
98643
S147
S
P
V
N
G
F
L
S
G
D
K
V
K
P
V
Rhesus Macaque
Macaca mulatta
XP_001113811
1015
110551
S251
L
P
I
N
G
L
L
S
G
D
K
V
K
P
V
Dog
Lupus familis
XP_532580
889
97932
S134
S
P
V
N
G
F
L
S
G
D
K
V
K
P
V
Cat
Felis silvestris
Mouse
Mus musculus
P42567
897
98453
S147
S
P
V
D
G
F
L
S
G
D
K
V
K
P
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026454
920
100691
S145
N
P
V
N
G
L
L
S
G
D
K
V
K
P
V
Frog
Xenopus laevis
O42287
1270
143652
P140
P
V
P
M
P
S
I
P
V
V
G
M
S
P
P
Zebra Danio
Brachydanio rerio
XP_002663145
1039
114340
T144
S
P
V
G
G
M
L
T
G
D
K
V
K
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001122937
1043
116535
P141
Q
P
S
N
G
Y
I
P
G
N
K
V
K
D
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192039
1179
125310
Q234
L
R
G
Q
I
S
S
Q
Q
S
N
V
K
K
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P34216
1381
150765
A154
A
K
G
A
Q
T
V
A
G
D
K
A
K
D
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
43.2
91.5
N.A.
89.3
N.A.
N.A.
N.A.
74.6
21
50.5
N.A.
N.A.
30.1
N.A.
29.6
Protein Similarity:
100
99.7
59.5
94.5
N.A.
93.4
N.A.
N.A.
N.A.
84.1
34.9
64.4
N.A.
N.A.
48.2
N.A.
44.3
P-Site Identity:
100
100
80
100
N.A.
93.3
N.A.
N.A.
N.A.
86.6
6.6
80
N.A.
N.A.
53.3
N.A.
13.3
P-Site Similarity:
100
100
86.6
100
N.A.
100
N.A.
N.A.
N.A.
93.3
20
86.6
N.A.
N.A.
73.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
10
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
73
0
0
0
19
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
37
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
19
10
73
0
0
0
82
0
10
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
10
0
10
0
19
0
0
0
0
0
0
0
10
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
82
0
91
10
10
% K
% Leu:
19
0
0
0
0
19
64
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
10
0
0
0
0
0
10
0
0
0
% M
% Asn:
10
0
0
55
0
0
0
0
0
10
10
0
0
0
0
% N
% Pro:
10
73
10
0
10
0
0
19
0
0
0
0
0
73
10
% P
% Gln:
10
0
0
10
10
0
0
10
10
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
46
0
10
0
0
19
10
55
0
10
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% T
% Val:
0
10
55
0
0
0
10
0
10
10
0
82
0
0
73
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _